Hearing Loss Programs

Developing Better Treatments For Hearing Loss

Our hearing loss small molecule drug discovery programs currently focus on inner hair cell regeneration.

We have developed new scientific techniques and gathered detailed knowledge of inner ear molecular biology to enable us to develop new drugs that can regenerate the lost hair cells and potentially restore a level of hearing. To make these new therapies as effective as possible, we’re also developing better ways to deliver them directly into the inner ear.

inner ear cochlea biology

Image by Dr. Sonja Pyott, University of North Carolina

Our developing broad IP portfolio encompasses new molecules, delivery systems and drug discovery tools for hearing and hearing loss research.  We have our own validated industrialized screening cascade and a critical path to identify, verify and develop new small molecule compounds which, together with our in-depth knowledge of inner ear biology and tools for hearing loss research, will enable us to progress these new compounds through the drug development process.

To date, Audion has identified several compounds that can regenerate hair cells in laboratory–based cell culture assays.

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